Fat-secreted molecule lowers response to common cancer treatment

Journal Reference: Arumugam Nagalingam, Sumit Siddharth, Sheetal Parida, Nethaji Muniraj, Dimiter Avtanski, Panjamurthy Kuppusamy, Justin Elsey, Jack L. Arbiser, Balázs Győrffy, Dipali Sharma. Hyperleptinemia in obese state renders luminal breast cancers refractory to tamoxifen by coordinating a crosstalk between Med1, miR205 and ErbB. npj Breast Cancer, 2021; 7 (1) DOI: 10.1038/s41523-021-00314-9 “Obese women may not … Read more

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