Virtual Reality could help make therapy easier

Journal Reference: Shane L. Rogers, Rebecca Broadbent, Jemma Brown, Alan Fraser, Craig P. Speelman. Realistic Motion Avatars are the Future for Social Interaction in Virtual Reality. Frontiers in Virtual Reality, 2022; 2 DOI: 10.3389/frvir.2021.750729 The Edith Cowan University (ECU) study found 30 per cent of people prefer to talk about negative experiences with a virtual … Read more

New gene therapy approach offers a potential long-term treatment for limb-girdle muscular dystrophy 2B

New gene therapy approach offers a potential long-term treatment for limb-girdle muscular dystrophy 2B – NovLink Home Mash S New gene therapy approach offers a potential long-term treatment for limb-girdle muscular dystrophy 2B We wish to give thanks to the author of this article for this outstanding material New gene therapy approach offers a potential … Read more

Gene Network changes associated with cancer onset and progression identify new candidates for targeted gene therapy

Gene Network changes associated with cancer onset and progression identify new candidates for targeted gene therapy – NovLink Home Mash S Gene Network changes associated with cancer onset and progression identify new candidates for targeted gene therapy We want to thank the writer of this write-up for this outstanding content Gene Network changes associated with … Read more

Experimental gene therapy reverses sickle cell disease for years

Journal Reference: Julie Kanter, Mark C. Walters, Lakshmanan Krishnamurti, Markus Y. Mapara, Janet L. Kwiatkowski, Stacey Rifkin-Zenenberg, Banu Aygun, Kimberly A. Kasow, Francis J. Pierciey, Melissa Bonner, Alex Miller, Xinyan Zhang, Jessie Lynch, Dennis Kim, Jean-Antoine Ribeil, Mohammed Asmal, Sunita Goyal, Alexis A. Thompson, John F. Tisdale. Biologic and Clinical Efficacy of LentiGlobin for Sickle … Read more

Gene therapy strategy found effective in mouse model of hereditary disease TSC

Journal Reference: Pike-See Cheah, Shilpa Prabhakar, David Yellen, Roberta L. Beauchamp, Xuan Zhang, Shingo Kasamatsu, Roderick T. Bronson, Elizabeth A. Thiele, David J. Kwiatkowski, Anat Stemmer-Rachamimov, Bence György, King-Hwa Ling, Masao Kaneki, Bakhos A. Tannous, Vijaya Ramesh, Casey A. Maguire, Xandra O. Breakefield. Gene therapy for tuberous sclerosis complex type 2 in a mouse model … Read more

Improved vectors for ocular gene therapy

Journal Reference: Marina Pavlou, Christian Schön, Laurence M Occelli, Axel Rossi, Nadja Meumann, Ryan F Boyd, Joshua T Bartoe, Jakob Siedlecki, Maximilian J Gerhardt, Sabrina Babutzka, Jacqueline Bogedein, Johanna E Wagner, Siegfried G Priglinger, Martin Biel, Simon M Petersen‐Jones, Hildegard Büning, Stylianos Michalakis. Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders. EMBO Molecular … Read more

Cellular benefits of gene therapy seen decades after treatment

Journal Reference: Natalia Izotova, Christine Rivat, Cristina Baricordi, Elena Blanco, Danilo Pellin, Eleanor Watt, Athina S. Gkazi, Stuart Adams, Kimberly Gilmour, Jinhua Bayford, Claire Booth, H. Bobby Gaspar, Adrian J. Thrasher, Luca Biasco. Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-21834-9 The research … Read more

Innovative gene therapy ‘reprograms’ cells to reverse neurological deficiencies

Journal Reference: Toni S. Pearson, Nalin Gupta, Waldy San Sebastian, Jill Imamura-Ching, Amy Viehoever, Ana Grijalvo-Perez, Alex J. Fay, Neha Seth, Shannon M. Lundy, Youngho Seo, Miguel Pampaloni, Keith Hyland, Erin Smith, Gardenia de Oliveira Barbosa, Jill C. Heathcock, Amy Minnema, Russell Lonser, J. Bradley Elder, Jeffrey Leonard, Paul Larson, Krystof S. Bankiewicz. Gene therapy … Read more

Scientists develop new gene therapy for eye disease

Journal Reference: Daniel M. Maloney, Naomi Chadderton, Sophia Millington-Ward, Arpad Palfi, Ciara Shortall, James J. O’Byrne, Lorraine Cassidy, David Keegan, Peter Humphries, Paul Kenna, Gwyneth Jane Farrar. Optimized OPA1 Isoforms 1 and 7 Provide Therapeutic Benefit in Models of Mitochondrial Dysfunction. Frontiers in Neuroscience, 2020; 14 DOI: 10.3389/fnins.2020.571479 The study, which involved a collaboration with … Read more

Glaucoma could be successfully treated with gene therapy

Journal Reference: Jiahui Wu, Oliver H. Bell, David A. Copland, Alison Young, John R. Pooley, Ryea Maswood, Rachel S. Evans, Peng Tee Khaw, Robin R. Ali, Andrew D. Dick, Colin J. Chu. Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9. Molecular Therapy, 2020; 28 (3): 820 DOI: 10.1016/j.ymthe.2019.12.012 Glaucoma affects over … Read more

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