Engineered nanomaterial captures off-target cancer drug to prevent tissue damage

Journal Reference: Sarah A.E. Young, Joy Muthami, Mica Pitcher, Petar Antovski, Patricia Wamea, Robert Denis Murphy, Reihaneh Haghniaz, Andrew Schmidt, Samuel Clark, Ali Khademhosseini, Amir Sheikhi. Engineering hairy cellulose nanocrystals for chemotherapy drug capture. Materials Today Chemistry, 2022; 23: 100711 DOI: 10.1016/j.mtchem.2021.100711 “To reduce the off-target effects of cancer drugs during and after localized chemotherapy, … Read more

An enemy inside: Pathogens hide in tissue

Journal Reference: Jiagui Li, Beatrice Claudi, Joseph Fanous, Natalia Chicherova, Francesca Romana Cianfanelli, Robert A. A. Campbell, Dirk Bumann. Tissue compartmentalization enables Salmonella persistence during chemotherapy. Proceedings of the National Academy of Sciences, 2021; 118 (51): e2113951118 DOI: 10.1073/pnas.2113951118 Infections such as tuberculosis or typhoid fever are caused by bacteria and can usually be treated … Read more

Soft tissue destruction and lower back pain

Journal Reference: Lei Liu, Kui Huang, Wei Li, Rongmao Qiu, Yijie Fang, Yongjie Huang, Suwen Zhao, Hai Lv, Kuibo Zhang, Hong Shan, Yang Li. Molecular Imaging of Collagen Destruction of the Spine. ACS Nano, 2021; DOI: 10.1021/acsnano.1c07112 Anywhere along the spine, from the neck to tail bone, can become uncomfortable when its soft and protective … Read more

Innovative silicon nanochip can reprogram biological tissue in living body

Journal Reference: Yi Xuan, Subhadip Ghatak, Andrew Clark, Zhigang Li, Savita Khanna, Dongmin Pak, Mangilal Agarwal, Sashwati Roy, Peter Duda, Chandan K. Sen. Fabrication and use of silicon hollow-needle arrays to achieve tissue nanotransfection in mouse tissue in vivo. Nature Protocols, 2021; 16 (12): 5707 DOI: 10.1038/s41596-021-00631-0 The technology, called tissue nanotransfection, is a non-invasive … Read more

Using 4D printing to enable vascularization, bone tissue regeneration, spinal fusion

Journal Reference: Hanjun Hwangbo, Hyeongjin Lee, Eun Ji Roh, WonJin Kim, Hari Prasad Joshi, Su Yeon Kwon, Un Yong Choi, In-Bo Han, Geun Hyung Kim. Bone tissue engineering via application of a collagen/hydroxyapatite 4D-printed biomimetic scaffold for spinal fusion. Applied Physics Reviews, 2021; 8 (2): 021403 DOI: 10.1063/5.0035601 While autogenous bone grafts have long been … Read more

Optoelectrode changes reduce injuries to brain tissue, improve nerve research

Journal Reference: Vittorino Lanzio, Vanessa Gutierrez, John Hermiz, Kristofer Bouchard, Stefano Cabrini. Neural optoelectrodes merging semiconductor scalability with polymeric-like bendability for low damage acute in vivo neuron readout and stimulation. Journal of Vacuum Science & Technology B, 2021; 39 (6): 063001 DOI: 10.1116/6.0001269 Researchers at Lawrence Berkeley National Laboratory developed a technique for assembling optoelectrodes … Read more

Nerves may be key to blocking abnormal bone growth in tissue

Journal Reference: Seungyong Lee, Charles Hwang, Simone Marini, Robert J. Tower, Qizhi Qin, Stefano Negri, Chase A. Pagani, Yuxiao Sun, David M. Stepien, Michael Sorkin, Carrie A. Kubiak, Noelle D. Visser, Carolyn A. Meyers, Yiyun Wang, Husain A. Rasheed, Jiajia Xu, Sarah Miller, Amanda K. Huber, Liliana Minichiello, Paul S. Cederna, Stephen W. P. Kemp, … Read more

Guidance on supplemental breast cancer screening for women with dense breast tissue

Journal Reference: Suneela Vegunta, Juliana M. Kling, Bhavika K. Patel. Supplemental Cancer Screening for Women With Dense Breasts: Guidance for Health Care Professionals. Mayo Clinic Proceedings, 2021; DOI: 10.1016/j.mayocp.2021.06.001 Breast cancer is the second most common cause of cancer death in women. Although 1 in 8 women will be affected by breast cancer, early detection … Read more

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